CAS No. 548-77-6
Batch:
Purity:99.74
Chemical Structure
Check the
Tectorigenin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 548-77-6 | |
|---|---|---|
| Molecular Formula |
C16H12O6 |
|
| Molecular Weight (MW) | 300.26 | |
| SMILES | COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O |
Biological Activity
Tectorigenin is a natural isoflavone that acts as a plant-derived bioactive compound with modulating activity on estrogen receptors and inflammatory signaling cascades. It suppresses lipopolysaccharide-induced inflammatory responses by inhibiting the NF-kB and MAPK pathways, leading to down-regulation of pro-inflammatory mediators such as inducible nitric oxide synthase and cyclooxygenase-2. Additionally, tectorigenin exhibits antitumor activity by inducing apoptosis and inhibiting cell proliferation in various cancer cell models.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(199.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.