CAS No. 13674-84-5

Batch: Purity:
TCPP Chemical Structure
Chemical Structure
Check the TCPP product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 13674-84-5
Molecular Formula

C9H18Cl3O4P

Molecular Weight (MW) 327.57
SMILES CC(CCl)O[P;v5](=O)(OC(C)CCl)OC(C)CCl

Ordering Information

Biological Activity

TCPP (Tris(2-chloroethyl) phosphate) is a chlorinated organophosphate flame retardant. Exposure to TCPP induces neurotoxic effects characterized by locomotor deficits, reduced crawling speed, and dopaminergic neuron degeneration in model organisms. In human peripheral blood mononuclear cells, TCPP triggers genomic instability by inducing DNA damage and altering global DNA methylation profiles, leading to cellular toxicity and impaired cellular homeostasis.[1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.