CAS No. 345909-26-4

Batch: Purity:98
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Taurocholic acid sodium salt hydrate Chemical Structure
Chemical Structure
Check the Taurocholic acid sodium salt hydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 345909-26-4
Molecular Formula

C26H45NO7S.xH2O.Na
Molecular Weight (MW) 537.68 (anhydrous basis)
SMILES CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O.[Na+]

Biological Activity

Taurocholic acid sodium salt hydrate is a conjugated bile acid salt synthesized in the liver through cholic acid conjugation with taurine. It plays a physiological role in lipid emulsification and solubilization within the digestive system. In preclinical research, taurocholic acid sodium salt is widely utilized to induce animal models of severe acute pancreatitis, leading to acinar cell injury, pancreatic edema, and systemic inflammatory responses. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Aho HJ, et al. Scand J Gastroenterol. 1980;15(4):417-24.

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Note: Technical data last updated: Sep 1, 2026.