CAS No. 519055-62-0
Batch:
Purity:99.93
Chemical Structure
Check the
Tasisulam
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 519055-62-0 | |
|---|---|---|
| Molecular Formula |
C11H6BrCl2NO3S2 |
|
| Molecular Weight (MW) | 415.11 | |
| SMILES | C1=CC(=C(C=C1Cl)Cl)C(=O)NS(=O)(=O)C2=CC=C(S2)Br |
Tasisulam (LY573636) is an acylsulfonamide antitumor agent that acts as a potent inducer of apoptosis through the intrinsic mitochondrial pathway. Disruption of mitochondrial membrane integrity triggers cytochrome c release and caspase activation, promoting downstream apoptotic signaling cascades. These molecular events lead to cell cycle arrest and execution of programmed cell death in neoplastic cells. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(199.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 83 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.