CAS No. 66898-62-2
| IUPAC Name | (3-oxo-1H-2-benzofuran-1-yl) 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate | |
|---|---|---|
| CAS Number | 66898-62-2 | |
| Molecular Formula |
C21H13F3N2O4 |
|
| Molecular Weight (MW) | 414.33 | |
| SMILES | C1=CC=C2C(=C1)C(OC2=O)OC(=O)C3=C(N=CC=C3)NC4=CC=CC(=C4)C(F)(F)F | |
| InChIKey | ANMLJLFWUCQGKZ-UHFFFAOYSA-N |
Talniflumate is an anti-inflammatory small molecule that acts as an inhibitor of human calcium-activated chloride channels. By blocking calcium-activated chloride channel activity, it functions as a mucin regulator to attenuate mucin production and suppress mucus hypersecretion. Consequently, this targeted modulation reduces airway mucus accumulation and mitigates inflammatory responses associated with respiratory conditions such as cystic fibrosis, chronic obstructive pulmonary disease, and asthma. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
10 mg/mL
(24.13 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
21 mg/mL
(50.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
20 mg/mL
(48.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.