SMILES:
CC1=C(C=C(S1)C(=O)C2=CN=CN=C2NC3CC(C(C3)O)COS(=O)(=O)N)C4C5=C(CCN4)C=CC(=C5)Cl
Chemical Structure
Check the
Subasumstat (TAK-981)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | [(1R,2S,4R)-4-[[5-[4-[(1R)-7-chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl]pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate | |
|---|---|---|
| CAS Number | 1858276-04-6 | |
| Molecular Formula |
C25H28ClN5O5S2 |
|
| Molecular Weight (MW) | 578.10 | |
| SMILES | CC1=C(C=C(S1)C(=O)C2=CN=CN=C2NC3CC(C(C3)O)COS(=O)(=O)N)C4C5=C(CCN4)C=CC(=C5)Cl | |
| InChIKey | LXRZVMYMQHNYJB-UNXOBOICSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(172.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(172.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(172.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 33 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(172.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 25 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Subasumstat (TAK-981) Mechanism of Action: SAE Inhibition in Tumor and Immune Cells Research
- Subasumstat (TAK-981) Clinical Trials
- Subasumstat (TAK-981) Working Concentration | Cell Culture | Treatment
- Subasumstat (TAK-981) Solubility in DMSO
- Subasumstat (TAK-981) Stock Solution
- Subasumstat (TAK-981) Storage
- Subasumstat (TAK-981) Stability
- Subasumstat (TAK-981) Combination Database
- Subasumstat (TAK-981) Molecular Weight
- Subasumstat (TAK-981) CAS Number
- Subasumstat (TAK-981) Chemical Structure (2D and 3D)
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- Subasumstat (TAK-981) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.