CAS No. 14215-86-2

Batch: Purity:99.84
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Sweroside Chemical Structure
Chemical Structure
Check the Sweroside product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (3S,4R,4aS)-4-ethenyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,4a,5,6-tetrahydro-3H-pyrano[3,4-c]pyran-8-one
CAS Number 14215-86-2
Molecular Formula

C16H22O9
Molecular Weight (MW) 358.34
SMILES C=CC1C2CCOC(=O)C2=COC1OC3C(C(C(C(O3)CO)O)O)O
InChIKey VSJGJMKGNMDJCI-ZASXJUAOSA-N

Biological Activity

Sweroside is a natural iridoid glucoside that exhibits anti-inflammatory, anti-diabetic, and hepatoprotective properties. It attenuates cellular signaling through the NF-kB and MAPK pathways, thereby suppressing pro-inflammatory cytokine production and decreasing oxidative stress. Downstream, these cellular modulations result in reduced tissue inflammation, enhanced osteoblast differentiation, and protection against metabolic dysfunctions in preclinical disease models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 10 mg/mL (27.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.