CAS No. 59-40-5

Batch: Purity:99.31
sulphaquinoxaline Chemical Structure
Chemical Structure
Check the sulphaquinoxaline product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 59-40-5
Molecular Formula

C14H12N4O2S

Molecular Weight (MW) 300.34

Ordering Information

Biological Activity

Sulfaquinoxaline is a sulfonamide antimicrobial agent that targets dihydropteroate synthase (DHPS) to inhibit de novo bacterial folic acid synthesis. By competitively blocking DHPS activity, it impairs downstream nucleotide biosynthesis and essential metabolic pathways, leading to the suppression of cell growth across a broad spectrum of Gram-positive and Gram-negative bacteria as well as coccidial parasites. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 60 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.