CAS No. 1212012-37-7

Batch: Purity:97
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Sulfosuccinimidyl Oleate Sodium (SSO) Chemical Structure
Chemical Structure
Check the Sulfosuccinimidyl Oleate Sodium (SSO) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium 1-[(Z)-octadec-9-enoyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
CAS Number 1212012-37-7
Molecular Formula

C22H37NO7S.Na
Molecular Weight (MW) 482.59
InChIKey FZVVLJSNKVOPRF-KVVVOXFISA-M

Biological Activity

Sulfosuccinimidyl oleate sodium is a long-chain fatty acid derivative that acts as a CD36-mediated fatty acid transport inhibitor and a potent, irreversible inhibitor of the mitochondrial respiratory chain with an IC50 of 4 μM. By targeting CD36 translocase and mitochondrial complex III, it disrupts intracellular lipid uptake, attenuates inflammatory enzyme expression, and produces neuroprotective and anti-inflammatory phenotypes in cell models.[1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 23 mg/mL (47.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 3 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Drahota Z, et al. Biochem Biophys Res Commun. 2010;391(3):1348-1351.

[2] Dhungana H, et al. J Neuroinflammation. 2017;14(1):237.

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Note: Technical data last updated: Sep 1, 2026.