CAS No. 60311-02-6
Batch:
Purity:99.62
Chemical Structure
Check the
Sulforhodamine 101
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 60311-02-6 | |
|---|---|---|
| Molecular Formula |
C31H30N2O7S2 |
|
| Molecular Weight (MW) | 606.72 | |
| SMILES | O[S](=O)(=O)C1=CC(=C(C=C1)C2=C3C=C4CCCN5CCCC(=C45)C3=[O+]C6=C7CCCN8CCCC(=C78)C=C26)[S]([O-])(=O)=O |
Biological Activity
Sulforhodamine 101 is a red fluorescent dye widely utilized as a selective marker for astroglia identification and visualization in intact neocortical tissue. Upon uptake by protoplasmic astrocytes, it enables high-contrast two-photon microscopy imaging to evaluate astroglial morphological characteristics and their anatomical association with the cortical microvasculature. This selective cellular labeling facilitates the functional analysis of astroglial networks and distinct calcium signaling dynamics in vivo without staining microglial cells. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(164.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.