CAS No. 967-80-6

Batch: Purity:98.21
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Sulfaquinoxaline sodium Chemical Structure
Chemical Structure
Check the Sulfaquinoxaline sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium (4-aminophenyl)sulfonyl-quinoxalin-2-ylazanide
CAS Number 967-80-6
Molecular Formula

C14H11N4O2S.Na
Molecular Weight (MW) 322.32
SMILES C1=CC=C2C(=C1)N=CC(=N2)[N-]S(=O)(=O)C3=CC=C(C=C3)N.[Na+]
InChIKey WXUQBKOBXREBBX-UHFFFAOYSA-N

Biological Activity

Sulfaquinoxaline sodium is a sulfonamide antimicrobial agent that acts as a competitive inhibitor of microbial dihydropteroate synthase to block folic acid biosynthesis. By inhibiting dihydropteroate synthase, it prevents the formation of essential precursor metabolites, leading to the downstream suppression of microbial nucleic acid and protein synthesis. This inhibition impairs cellular proliferation and microbial replication, displaying broad anticoccidial and antibacterial activity. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 32 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Achari A, et al. Nat Struct Biol. 1997;4(6):490-7.

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Note: Technical data last updated: Sep 1, 2026.