CAS No. 69388-79-0
Batch:
Purity:98.65
Chemical Structure
Check the
Sulbactam pivoxil
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2,2-dimethylpropanoyloxymethyl (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | |
|---|---|---|
| CAS Number | 69388-79-0 | |
| Molecular Formula |
C14H21NO7S |
|
| Molecular Weight (MW) | 347.39 | |
| InChIKey | OHPVYKXTRACOSQ-ZJUUUORDSA-N |
Biological Activity
Sulbactam pivoxil (CP 47904) is an orally bioavailable prodrug of sulbactam that acts as an inhibitor of β-lactamase. Upon administration, sulbactam pivoxil achieves superior intestinal absorption compared to parent sulbactam, producing high systemic levels. By inhibiting bacterial β-lactamase enzymes, it protects co-administered β-lactam antibiotics from enzymatic degradation and restores their bactericidal activity against β-lactamase-producing resistant bacterial strains. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
69 mg/mL
(198.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 8 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.