CAS No. 842-07-9
Batch:
Purity:99.84
Chemical Structure
Check the
Sudan I
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 1-phenyldiazenylnaphthalen-2-ol | |
|---|---|---|
| CAS Number | 842-07-9 | |
| Molecular Formula |
C16H12N2O |
|
| Molecular Weight (MW) | 248.28 | |
| SMILES | C1=CC=C(C=C1)N=NC2=C(C=CC3=CC=CC=C32)O | |
| InChIKey | MRQIXHXHHPWVIL-UHFFFAOYSA-N |
Biological Activity
Sudan I is a synthetic azo dye and xenobiotic compound that undergoes bioactivation catalyzed by cytochrome P450 enzymes, particularly CYP1A1 and CYP1A2, as well as peroxidases. Metabolism of Sudan I generates reactive electrophilic intermediates, leading to covalent DNA adduct formation, oxidative stress, and mutagenicity. These downstream events disrupt genomic integrity and trigger oncogenic signaling pathways, ultimately contributing to tumorigenesis in hepatic and urinary bladder tissues.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
13 mg/mL
(52.36 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.