CAS No. 864167-45-3
Chemical Structure
Check the
Succinyl phosphonate trisodium salt
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | trisodium;4-oxo-4-phosphonatobutanoate | |
|---|---|---|
| CAS Number | 864167-45-3 | |
| Molecular Formula |
C4H7O6P.3Na |
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| Molecular Weight (MW) | 251.04 | |
| InChIKey | QHBOYEUINLIJDF-UHFFFAOYSA-K |
Succinyl phosphonate trisodium salt is a selective inhibitor of the α-ketoglutarate dehydrogenase complex (KGDHC). By inhibiting KGDHC activity and reducing succinyl-CoA-dependent protein succinylation, it modulates mitochondrial energy metabolism in brain tissue and cultured cells. Consequently, KGDHC inhibition alters cellular redox state, reduces mitochondrial reactive oxygen species production, and protects neurons against metabolic stress and neurotoxicity. [1]
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- Succinyl phosphonate trisodium salt Solubility in DMSO
- Succinyl phosphonate trisodium salt Stock Solution
- Succinyl phosphonate trisodium salt Storage
- Succinyl phosphonate trisodium salt Stability
- Succinyl phosphonate trisodium salt Molecular Weight
- Succinyl phosphonate trisodium salt Chemical Structure (2D and 3D)
- Succinyl phosphonate trisodium salt SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.