CAS No. 23141-25-5
Batch:
Purity:99.99
Chemical Structure
Check the
Strictosamide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 23141-25-5 | |
|---|---|---|
| Molecular Formula |
C26H30N2O8 |
|
| Molecular Weight (MW) | 498.52 |
Strictosamide is a natural monoterpene indole alkaloid that exhibits anti-inflammatory and analgesic properties. It inhibits the activation of NF-kB and MAPK signaling pathways, thereby downregulating key pro-inflammatory mediators including nitric oxide, TNF-α, and IL-1β in macrophages. Consequently, strictosamide suppresses systemic cellular inflammation, reducing acute tissue edema, microvascular permeability, and nociceptive pain responses in vivo. [1][2]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(200.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.