CAS No. 2361304-26-7

STAT3-IN-3 Chemical Structure
Chemical Structure
Check the STAT3-IN-3 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 3-[4-(4-bromo-1,1-dioxo-1-benzothiophene-2-carbonyl)piperazine-1-carbonyl]-7-(diethylamino)chromen-2-one
CAS Number 2361304-26-7
Molecular Formula

C27H26BrN3O6S
Molecular Weight (MW) 600.48
InChIKey LEVMMUZFAXTJOJ-UHFFFAOYSA-N

Biological Activity

STAT3-IN-3 is a potent and selective inhibitor of Signal Transducer and Activator of Transcription 3 (STAT3). By targeting STAT3, it disrupts STAT3-mediated signaling pathways, suppressing downstream gene expression involved in cell proliferation, survival, and oncogenesis. Inhibition of this signaling axis modulates key cellular functions and shows efficacy in overcoming drug resistance in cancer models. [1]

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Reference

[1] Yu H, et al. Nat Rev Cancer. 2014;14(11):736-46.

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Note: Technical data last updated: Sep 1, 2026.