CAS No. 179248-59-0
Batch:
Purity:99.06
Chemical Structure
Check the
Src Inhibitor 1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine | |
|---|---|---|
| CAS Number | 179248-59-0 | |
| Molecular Formula |
C22H19N3O3 |
|
| Molecular Weight (MW) | 373.40 | |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC | |
| InChIKey | DMWVGXGXHPOEPT-UHFFFAOYSA-N |
Src Inhibitor 1 is a potent competitive inhibitor of Src family kinases, targeting Src and Lck as well as Csk and Yes. By inhibiting Src tyrosine kinase activity, it disrupts downstream signaling pathways including STAT3, PI3K/AKT, and MAPK/ERK. This targeted inhibition suppresses cellular proliferation, impairs cell migration and invasion, and alters immune cell functional phenotypes. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
9 mg/mL
(24.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
25 mg/mL
(66.95 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.