CAS No. 174689-39-5
Batch:
Purity:99.46
Chemical Structure
Check the
SR59230A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-1-(2-ethylphenoxy)-3-[[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]propan-2-ol;oxalic acid | |
|---|---|---|
| CAS Number | 174689-39-5 | |
| Molecular Formula |
C23H29NO6 |
|
| Molecular Weight (MW) | 415.48 | |
| SMILES | CCC1=CC=CC=C1OCC(CNC2CCCC3=CC=CC=C23)O.C(=O)(C(=O)O)O | |
| InChIKey | XTBQNQMNFXNGLR-MKSBGGEFSA-N |
SR59230A is a blood-brain barrier-penetrating, selective antagonist of the β3-adrenergic receptor (IC50 40 nM), β1-adrenergic receptor (IC50 408 nM), and β2-adrenergic receptor (IC50 648 nM). By blocking β3-adrenergic receptors, it inhibits downstream cAMP signaling and modulates lipid metabolism and thermogenic pathways, providing a key pharmacological probe to investigate peripheral and central adrenergic receptor functions.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 10 mg/mL |
| Water | Insoluble |
| DMSO |
83 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.