CAS No. 160162-42-5
Batch:
Purity:96.04
Chemical Structure
Check the
SR 11302
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid | |
|---|---|---|
| CAS Number | 160162-42-5 | |
| Molecular Formula |
C26H32O2 |
|
| Molecular Weight (MW) | 376.53 | |
| SMILES | O=C(O)/C=C(C)/C=C/C=C(C1=CC=C(C)C=C1)/C=C/C2=C(C)CCCC2(C)C | |
| InChIKey | RQANARBNMTXCDM-DKOHIBGUSA-N |
SR 11302 is a synthetic retinoid compound that acts as a selective inhibitor of activator protein-1 (AP-1) transcriptional activity. It suppresses AP-1-mediated gene transcription while sparing retinoic acid response element (RARE)-dependent transactivation. By targeting AP-1 signaling pathways, SR 11302 effectively modulates downstream cellular processes including cell proliferation, transformation, and inflammatory responses without triggering classical retinoid receptor transactivation. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
75 mg/mL
(199.18 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.