CAS No. 306-67-2
Batch:
Purity:98
Chemical Structure
Check the
Spermine Tetrahydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 306-67-2 | |
|---|---|---|
| Molecular Formula |
C10H26N4.4HCl |
|
| Molecular Weight (MW) | 348.18 | |
| SMILES | C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl |
Spermine tetrahydrochloride is an endogenous polyamine involved in cellular metabolism across all eukaryotic cells. It interacts with nucleic acids and cellular membranes, stabilizing DNA structure and protecting against free radical-mediated oxidative damage. Additionally, spermine modulates protein synthesis and ion channel activity, regulating cell growth, differentiation, and survival under various physiological and stress conditions. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 69 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Spermine Tetrahydrochloride Solubility in DMSO
- Spermine Tetrahydrochloride Stock Solution
- Spermine Tetrahydrochloride Storage
- Spermine Tetrahydrochloride Stability
- Spermine Tetrahydrochloride Molecular Weight
- Spermine Tetrahydrochloride SMILES
- Spermine Tetrahydrochloride Chemical Structure (2D and 3D)
- Spermine Tetrahydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.