SP600125 is a potent, selective, and reversible ATP-competitive JNK inhibitor. It affects JNK/c-Jun and MAPK signaling pathways by blocking JNK phosphorylation and c-Jun activation, effectively inhibiting inflammation, cell proliferation, and apoptosis in various cells.
SP600125 Mechanism of Action: JNK Inhibition in Cancer Cell Research
SP600125 MOA：Targeting JNK/MAPK for Oncology