SMILES:
CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O
Chemical Structure
Check the
Sotuletinib (BLZ945)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide | |
|---|---|---|
| CAS Number | 953769-46-5 | |
| Molecular Formula |
C20H22N4O3S |
|
| Molecular Weight (MW) | 398.48 | |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O | |
| InChIKey | ADZBMFGQQWPHMJ-RHSMWYFYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
80 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
| DMSO |
80 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | ˂1 mg/mL |
| DMSO |
80 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
80 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Sotuletinib (BLZ945) Mechanism of Action: CSF-1R Inhibition in Tumor-Associated Macrophage Research
- Sotuletinib (BLZ945) Clinical Trials
- Sotuletinib (BLZ945): Selectivity & Specificity
- Sotuletinib (BLZ945) Working Concentration | Cell Culture | Treatment
- Sotuletinib (BLZ945) Solubility in DMSO
- Sotuletinib (BLZ945) Stock Solution
- Sotuletinib (BLZ945) Storage
- Sotuletinib (BLZ945) Stability
- Sotuletinib (BLZ945) Combination Database
- Sotuletinib (BLZ945) Molecular Weight
- Sotuletinib (BLZ945) CAS Number
- Sotuletinib (BLZ945) Chemical Structure (2D and 3D)
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- Sotuletinib (BLZ945) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.