CAS No. 70142-34-6

Solutol HS-15 (Polyethylene glycol 12-hydroxystearate) Chemical Structure
Chemical Structure
Check the Solutol HS-15 (Polyethylene glycol 12-hydroxystearate) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 70142-34-6
Molecular Formula

C2H6O2*C18H36O3

Molecular Weight (MW) 362.55

Biological Activity

Solutol HS-15 (Polyethylene glycol 12-hydroxystearate) is a non-ionic surfactant and mucosal permeation enhancer that improves membrane permeability by disrupting plasma membrane structure. Disruption of plasma membrane organization reverses multidrug resistance phenotypes by inhibiting P-glycoprotein-mediated drug efflux. Furthermore, modulation of cell membrane fluidity alters endocytosis rates and tight junction dynamics, leading to enhanced transmucosal drug absorption across epithelial cell layers. [1][2]

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Note: Technical data last updated: Sep 1, 2026.