CAS No. 35807-85-3

Batch: Purity:99.47
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Sodium Tauroursodeoxycholate (TUDC) Chemical Structure
Chemical Structure
Check the Sodium Tauroursodeoxycholate (TUDC) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium 2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate
CAS Number 35807-85-3
Molecular Formula

C26H44NNaO6S
Molecular Weight (MW) 521.69
SMILES CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C.[Na+]
InChIKey IYPNVUSIMGAJFC-JUWYWQLMSA-M

Ordering Information

Biological Activity

Sodium Tauroursodeoxycholate (TUDC) is a naturally occurring hydrophilic bile acid salt that acts as a chemical chaperone and endoplasmic reticulum (ER) stress inhibitor. By reducing protein aggregation and suppressing unfolded protein response (UPR) pathway activation, it prevents ER stress-induced apoptosis, restores insulin sensitivity, and protects cells against cellular injury across various metabolic and neurodegenerative disease models. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (191.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 46 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.