CAS No. 41945-48-6

Batch: Purity:98.54
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Sodium tauroglycocholate Chemical Structure
Chemical Structure
Check the Sodium tauroglycocholate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 41945-48-6
Molecular Formula

C28H47N2NaO8S
Molecular Weight (MW) 594.74
SMILES [Na+].CC(CCC(=O)NCC(=O)NCC[S]([O-])(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C

Ordering Information

Biological Activity

Sodium tauroglycocholate is a bile salt derivative that acts as a drug absorption enhancer. It alters intercellular lipid structures and increases membrane fluidity, thereby facilitating the transdermal permeation and mucosal transport of various therapeutic compounds. Through these membrane-modulating properties, sodium tauroglycocholate significantly enhances the flux and bioavailability of poorly permeable active pharmaceutical ingredients in drug delivery applications.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (168.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 10 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.