CAS No. 547-32-0
Batch:
Purity:99.90
Chemical Structure
Check the
Sodium sulfadiazine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 547-32-0 | |
|---|---|---|
| Molecular Formula |
C10H10N4O2S.Na |
|
| Molecular Weight (MW) | 272.26 | |
| SMILES | C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+] |
Sodium sulfadiazine is a bacteriostatic synthetic sulfanilamide derivative that functions as a competitive inhibitor of dihydropteroate synthase (DHPS). By inhibiting DHPS, it blocks the bacterial and protozoal de novo biosynthesis of folic acid. This disruption impairs downstream purine and pyrimidine nucleotide synthesis, thereby suppressing microbial nucleic acid assembly, cell division, and overall microbial proliferation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 54 mg/mL |
| DMSO |
9 mg/mL
(33.05 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.