CAS No. 408-35-5
Batch:
Purity:97
Chemical Structure
Check the
Sodium palmitate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium hexadecanoate | |
|---|---|---|
| CAS Number | 408-35-5 | |
| Molecular Formula |
C16H32O2.Na |
|
| Molecular Weight (MW) | 279.41 | |
| InChIKey | GGXKEBACDBNFAF-UHFFFAOYSA-M |
Sodium palmitate is a long-chain saturated fatty acid involved in lipid metabolism and fatty acid synthesis. It enhances cellular steatosis and lipogenesis in various cell lines. Sodium palmitate activates glycogen synthase kinase-3β (GSK-3β) signaling, inducing c-Jun N-terminal kinase (JNK) phosphorylation and Bax upregulation. Furthermore, it elevates reactive oxygen species (ROS) generation, leading to intracellular lipid accumulation, impaired cell viability, and lipoapoptosis in hepatocytes.[1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| 50%Alcohol | 13 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.