CAS No. 14402-89-2

Batch: Purity:99.93
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Sodium nitroprusside Chemical Structure
Chemical Structure
Check the Sodium nitroprusside product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name disodium;azanylidyneoxidanium;iron(2+);pentacyanide
CAS Number 14402-89-2
Molecular Formula

C5FeN6O.2Na
Molecular Weight (MW) 261.92
SMILES [Na+].[Na+].[Fe++](|[C-]#N)(|[C-]#N)(|[C-]#N)(|[C-]#N)(|[C-]#N)|N#[O+]
InChIKey XEYBHCRIKKKOSS-UHFFFAOYSA-N

Ordering Information

Biological Activity

Sodium nitroprusside is a potent vasodilator and nitric oxide donor. Upon metabolization, it releases nitric oxide, which stimulates soluble guanylyl cyclase to increase intracellular cyclic GMP levels in vascular smooth muscle cells. This signaling pathway promotes vascular smooth muscle relaxation, resulting in the dilation of cerebral vessels and increased internal carotid artery blood flow. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 52 mg/mL (198.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 52 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.