CAS No. 13755-38-9
Batch:
Purity:99.7
Chemical Structure
Check the
Sodium Nitroprusside Dihydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | disodium;iron(4+);nitroxyl anion;pentacyanide;dihydrate | |
|---|---|---|
| CAS Number | 13755-38-9 | |
| Molecular Formula |
C5H4FeN6Na2O3 |
|
| Molecular Weight (MW) | 297.95 | |
| SMILES | [C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[N-]=O.O.O.[Na+].[Na+].[Fe+4] | |
| InChIKey | XRKMNJXYOFSTBE-UHFFFAOYSA-N |
Biological Activity
Sodium nitroprusside dihydrate is a potent antihypertensive agent and vasodilator that functions as a nitric oxide (NO) donor. Upon breakdown, it spontaneously releases NO in the vasculature, which directly stimulates soluble guanylyl cyclase (sGC). This enzymatic activation elevates intracellular cyclic GMP (cGMP) levels, activating protein kinase G and promoting vascular smooth muscle relaxation, leading to rapid blood vessel dilation and reduced peripheral vascular resistance. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(201.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 60 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
Jump to
- Sodium Nitroprusside Dihydrate Clinical Trials
- Sodium Nitroprusside Dihydrate Solubility in DMSO
- Sodium Nitroprusside Dihydrate Stock Solution
- Sodium Nitroprusside Dihydrate Storage
- Sodium Nitroprusside Dihydrate Stability
- Sodium Nitroprusside Dihydrate Molecular Weight
- Sodium Nitroprusside Dihydrate SMILES
- Sodium Nitroprusside Dihydrate Chemical Structure (2D and 3D)
- Sodium Nitroprusside Dihydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.