CAS No. 12141-67-2
Batch:
Purity:98
Chemical Structure
Check the
SodiuM Metatungstate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | hexasodium;tris(dioxido(dioxo)tungsten);nonakis(trioxotungsten) | |
|---|---|---|
| CAS Number | 12141-67-2 | |
| Molecular Formula |
H2O40W12.6Na |
|
| Molecular Weight (MW) | 2986.01 | |
| SMILES | O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W]( | |
| InChIKey | AZCSOJKJFMWYCX-UHFFFAOYSA-N |
Sodium metatungstate is an inorganic polyoxotungstate and potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDases, CD39), targeting NTPDase1, NTPDase2, and NTPDase3. By inhibiting enzymatic hydrolysis of extracellular ATP and ADP, it disrupts purinergic signaling cascades, suppressing downstream extracellular adenosine accumulation. This pathway inhibition modulates cellular inflammatory responses, immune cell activation, and vascular tone across various physiological cellular systems. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 50 mg/mL |
| DMSO |
30 mg/mL
(10.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.