CAS No. 66170-10-3

Batch: Purity:99.87
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Sodium L-Ascorbyl-2-Phosphate (SAP) Chemical Structure
Chemical Structure
Check the Sodium L-Ascorbyl-2-Phosphate (SAP) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name trisodium;[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-oxido-5-oxo-2H-furan-4-yl] phosphate
CAS Number 66170-10-3
Molecular Formula

C6H6O9P.3Na
Molecular Weight (MW) 322.05
SMILES C(C(C1C(=C(C(=O)O1)OP(=O)([O-])[O-])O)O)O.[Na+].[Na+]
InChIKey YRWWOAFMPXPHEJ-OFBPEYICSA-K

Ordering Information

Biological Activity

Sodium L-ascorbyl-2-phosphate is a stabilized vitamin C derivative that acts as a selective antioxidant and stimulator of hepatocyte growth factor production. By providing a sustained supply of bioactive ascorbic acid, it promotes extracellular matrix accumulation through enhanced collagen synthesis and cellular proliferation. Additionally, its antioxidant activity neutralizes reactive oxygen species to suppress oxidative stress and inhibit melanogenesis. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 64 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.