CAS No. 6223-35-4
Batch:
Purity:99.08
Chemical Structure
Check the
Sodium gualenate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 6223-35-4 | |
|---|---|---|
| Molecular Formula |
C15H17O3S.Na |
|
| Molecular Weight (MW) | 300.35 | |
| SMILES | CC1=C2C(=CC(=C2C=C(C=C1)C(C)C)C)S(=O)(=O)[O-].[Na+] |
Sodium gualenate is a hydrophilic derivative of guaiazulene that functions as an anti-inflammatory and mucosal protective agent. It modulates cellular inflammatory responses and attenuates tissue damage by regulating key inflammatory pathways, including NF-kB signaling. These actions lead to the suppression of inflammatory mediator release, reduction of mucosal lesions, and acceleration of wound healing and tissue repair processes in epithelial and mucosal tissues.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 18 mg/mL |
| Ethanol | 1 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.