CAS No. 145-41-5

Batch: Purity:99.45
Sodium Dehydrocholate Chemical Structure
Chemical Structure
Check the Sodium Dehydrocholate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 145-41-5
Molecular Formula

C24H33NaO5

Molecular Weight (MW) 424.51
SMILES CC(CCC(=O)[O-])C1CCC2C1(C(=O)CC3C2C(=O)CC4C3(CCC(=O)C4)C)C.[Na+]

Ordering Information

Biological Activity

Sodium Dehydrocholate is a semisynthetic bile acid derived from cholic acid that functions as a hydrocholeretic agent. It effectively stimulates hepatic bile flow and promotes biliary lipid secretion into the canalicular network. By inducing fluid secretion into bile without markedly increasing micellar bile acid concentrations, it enhances overall bile volume and supports downstream hepatic transport and excretory pathways. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 85 mg/mL (200.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.