CAS No. 6505-45-9
Batch:
Purity:99.81
Chemical Structure
Check the
Sodium 2-(1H-indol-3-yl)acetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 6505-45-9 | |
|---|---|---|
| Molecular Formula |
C10H8NNaO2 |
|
| Molecular Weight (MW) | 197.17 | |
| SMILES | [Na+].[O-]C(=O)CC1=C[NH]C2=CC=CC=C12 |
Sodium 2-(1H-indol-3-yl)acetate (3-Indoleacetic acid sodium) is an endogenous metabolite and natural auxin plant hormone. It serves as a key inducing ligand in the auxin-inducible degron system to trigger rapid ubiquitin-mediated proteasomal degradation of target proteins in mammalian cells. This pathway enables precise conditional protein knockdown to investigate downstream signal transduction and cell proliferation phenotypes. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
39 mg/mL
(197.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 39 mg/mL |
| Ethanol | 39 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Sodium 2-(1H-indol-3-yl)acetate Solubility in DMSO
- Sodium 2-(1H-indol-3-yl)acetate Stock Solution
- Sodium 2-(1H-indol-3-yl)acetate Storage
- Sodium 2-(1H-indol-3-yl)acetate Stability
- Sodium 2-(1H-indol-3-yl)acetate Molecular Weight
- Sodium 2-(1H-indol-3-yl)acetate SMILES
- Sodium 2-(1H-indol-3-yl)acetate Chemical Structure (2D and 3D)
- Sodium 2-(1H-indol-3-yl)acetate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.