CAS No. 1781934-47-1
Batch:
Purity:99.97
Chemical Structure
Check the
SNAP94847 hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1781934-47-1 | |
|---|---|---|
| Molecular Formula |
C29H33ClF2N2O2 |
|
| Molecular Weight (MW) | 515.00 | |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C(C)C)C2CCN(CC2)CC3=CC=C(C=C3)OC4=CC(=C(C=C4)F)F.Cl |
SNAP94847 hydrochloride is a high-affinity, selective antagonist of melanin-concentrating hormone receptor 1 (MCH1R). By blocking MCH receptor activation, it inhibits downstream G protein-coupled signaling cascades and intracellular calcium mobilization. This inhibition modulates MCH-driven neuroendocrine signaling, resulting in altered behavioral phenotypes in preclinical models of anxiety and depression. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
96 mg/mL
(186.4 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 96 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- SNAP94847 hydrochloride Solubility in DMSO
- SNAP94847 hydrochloride Stock Solution
- SNAP94847 hydrochloride Storage
- SNAP94847 hydrochloride Stability
- SNAP94847 hydrochloride Molecular Weight
- SNAP94847 hydrochloride SMILES
- SNAP94847 hydrochloride Chemical Structure (2D and 3D)
- SNAP94847 hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.