CAS No. 425613-09-8

Batch: Purity:99.27
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SJ000291942 Chemical Structure
Chemical Structure
Check the SJ000291942 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-(4-ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)acetamide
CAS Number 425613-09-8
Molecular Formula

C16H15FN2O4
Molecular Weight (MW) 318.30
SMILES CCC1=CC=C(C=C1)OCC(=O)NC2=CC(=C(C=C2)F)[N+](=O)[O-]
InChIKey YSZJLXPXVFGTNK-UHFFFAOYSA-N

Ordering Information

Biological Activity

SJ000291942 is a small-molecule activator of the canonical bone morphogenetic protein (BMP) signaling pathway. Through activation of BMP receptor-mediated cascades, the compound promotes the phosphorylation and nuclear translocation of Smad1, Smad5, and Smad8 proteins. This downstream signaling event drives transcriptional regulation of BMP-responsive target genes, modulating key biological processes including osteogenic differentiation, cellular fate determination, and tissue development.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 64 mg/mL (201.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 12 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.