CAS No. 7431-77-8

Batch: Purity:99.85
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Sinapine thiocyanate Chemical Structure
Chemical Structure
Check the Sinapine thiocyanate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 7431-77-8
Molecular Formula

C17H24N2O5S
Molecular Weight (MW) 368.45

Biological Activity

Sinapine thiocyanate is a naturally derived alkaloid salt that acts as an antioxidant and radioprotective agent. By suppressing cellular reactive oxygen species accumulation and inhibiting acetylcholinesterase activity, it modulates key signaling cascades including the NF-κB and Nrf2 pathways. This modulation reduces oxidative stress, attenuates inflammatory responses, and protects tissues from radiation-induced cellular injury.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 73 mg/mL (198.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.