CAS No. 80681-44-3

Batch: Purity:99.92
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Sec-O-Glucosylhamaudol Chemical Structure
Chemical Structure
Check the Sec-O-Glucosylhamaudol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 80681-44-3
Molecular Formula

C21H26O10
Molecular Weight (MW) 438.43
SMILES CC1=CC(=O)C2=C(C3=C(C=C2O1)OC(C(C3)OC4C(C(C(C(O4)CO)O)O)O)(C)C)O

Ordering Information

Biological Activity

Sec-O-Glucosylhamaudol is a major bioactive chromone glucoside isolated from Saposhnikoviae Radix with anti-inflammatory and analgesic activities. It suppresses inflammatory signaling cascades, leading to reduced expression of pro-inflammatory mediators and cytokines through modulation of the NF-kB pathway. These actions result in attenuated inflammatory responses and pain relief in cellular and animal models.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 89 mg/mL (202.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.