CAS No. 6106-81-6

Batch: Purity:98
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Scopolamine N-Oxide HydrobroMide Monohydrate Chemical Structure
Chemical Structure
Check the Scopolamine N-Oxide HydrobroMide Monohydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6106-81-6
Molecular Formula

C17H24BrNO6
Molecular Weight (MW) 418.28
SMILES C[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)[O-].Br

Ordering Information

Biological Activity

Scopolamine N-Oxide (Hyoscine N-oxide) is a muscarinic receptor antagonist used to investigate the binding characteristics and pharmacological properties of muscarinic cholinergic receptors. By blocking muscarinic acetylcholine receptors, it inhibits downstream cholinergic signaling pathways. This competitive blockade prevents acetylcholine-mediated cellular responses and physiological phenotypes, making it a valuable tool for studying parasympathetic nervous system pathways and cholinergic neurotransmission. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 84 mg/mL (200.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 7 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.