CAS No. 58546-54-6
Batch:
Purity:99.82
Chemical Structure
Check the
Schizandrol B
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 58546-54-6 | |
|---|---|---|
| Molecular Formula |
C23H28O7 |
|
| Molecular Weight (MW) | 416.46 | |
| SMILES | CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1(C)O)OC)OC)OC)OC)OCO3 |
Schizandrol B (Gomisin A) is a natural dibenzocyclooctadiene lignan isolated from Schisandra chinensis Baill. that exhibits potent antitumor and anti-inflammatory activities. It modulates key cellular signaling cascades, including the NF-kB and MAPK pathways, to attenuate pro-inflammatory mediator expression and suppress tumor cell proliferation. These pathway alterations subsequently lead to the inhibition of cell survival and the promotion of apoptotic phenotypes in targeted cancer models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(199.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
83 mg/mL
(199.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.