CAS No. 58546-55-7
Batch:
Purity:99.95
Chemical Structure
Check the
Schisantherin B
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 58546-55-7 | |
|---|---|---|
| Molecular Formula |
C28H34O9 |
|
| Molecular Weight (MW) | 514.56 | |
| SMILES | COC1=C(OC)C(=C2C(=C1)C(OC(=O)\C(C)=C/C)C(C)(O)C(C)CC3=C2C(=C4OCOC4=C3)OC)OC |
Biological Activity
Schisantherin B is a natural bioactive dibenzocyclooctadiene lignan isolated from Schisandra chinensis with anti-inflammatory and antioxidant activities. It attenuates cellular inflammatory responses by inhibiting the NF-kB and MAPK signaling pathways, leading to reduced production of pro-inflammatory cytokines such as TNF-α and IL-6. Additionally, Schisantherin B modulates cytochrome P450 enzyme activity and protects cells against oxidative stress-induced injury. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(194.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(194.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.