CAS No. 69363-14-0

Batch: Purity:99.92
Schisanhenol Chemical Structure
Chemical Structure
Check the Schisanhenol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (9S,10R)-4,5,14,15,16-pentamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-3-ol
CAS Number 69363-14-0
Molecular Formula

C23H30O6

Molecular Weight (MW) 402.48
SMILES CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)O)OC)OC
InChIKey FYSHYFPJBONYCQ-QWHCGFSZSA-N

Ordering Information

Biological Activity

Schisanhenol is a natural lignan compound that acts as an inhibitor of UDP-glucuronosyltransferase 2B7 (UGT2B7). By blocking UGT2B7 activity, it modulates the glucuronidation and metabolic clearance of various xenobiotics and endogenous substances within drug metabolism pathways. Additionally, schisanhenol exhibits potent antioxidant properties, attenuating reactive oxygen species generation and protecting cells against oxidative stress-induced cellular damage. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 82 mg/mL (203.73 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.