CAS No. 51938-32-0

Batch: Purity:99.94
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Schaftoside Chemical Structure
Chemical Structure
Check the Schaftoside product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one
CAS Number 51938-32-0
Molecular Formula

C26H28O14
Molecular Weight (MW) 564.49
SMILES C1C(C(C(C(O1)C2=C3C(=C(C(=C2O)C4C(C(C(C(O4)CO)O)O)O)O)C(=O)C=C(O3)C5=CC=C(C=C5)O)O)O)O
InChIKey MMDUKUSNQNWVET-VYUBKLCTSA-N

Biological Activity

Schaftoside is a natural bioactive flavonoid glycoside that acts as a pancreatic lipase inhibitor and target modulator in inflammatory pathways. It suppresses the expression of TLR4 and MyD88, leading to the downregulation of downstream NF-κB signaling and inflammatory cascades. Furthermore, Schaftoside decreases Drp1 expression and phosphorylation, which attenuates excessive mitochondrial fission and maintains cellular homeostasis.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (177.15 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.