CAS No. 1541209-75-9
| IUPAC Name | sodium 3-naphthalen-1-yloxycarbonyl-2,4-diphenylcyclobutane-1-carboxylate | |
|---|---|---|
| CAS Number | 1541209-75-9 | |
| Molecular Formula |
C28H22O4 |
|
| Molecular Weight (MW) | 422.47 | |
| SMILES | OC(=O)C1C(C(C1C2=CC=CC=C2)C(=O)OC3=C4C=CC=CC4=CC=C3)C5=CC=CC=C5 | |
| InChIKey | FNDYRXBMOVWBAD-UHFFFAOYSA-M |
SBFI-26 is a competitive small-molecule inhibitor targeting fatty acid-binding protein 5 (FABP5) and fatty acid-binding protein 7 (FABP7). By blocking FABP-mediated intracellular transport, SBFI-26 impairs the cellular uptake and breakdown of endocannabinoids, thereby increasing anandamide signaling. Downstream, this inhibition attenuates inflammatory pain pathways, reduces nociceptive behaviors in preclinical models, and suppresses prostate cancer cell proliferation and cell migration. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
84 mg/mL
(198.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
84 mg/mL
(198.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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