CAS No. 182410-00-0
Chemical Information
| CAS Number | 182410-00-0 | |
|---|---|---|
| Molecular Formula |
C42H70-nO35.nNa.n(C4H8O3S) |
|
| SMILES | [Na+].[Na+].OCC1OC2OC3C(O)C(O)C(OC3CO)OC4C(O)C(O)C(OC4CO)OC5C(O)C(OCCCC[S]([O-])(=O)=O)C(OC5COCCCC[S]([O-])(=O)=O)OC6=C(CO)OC(OC7C(O)C(O)C(OC7CO)OC8C(O)C(O)C(OC8CO)OC1C(O)C2O)C(O)C6O |
Biological Activity
SBE-β-CD (Sulfobutylether-β-cyclodextrin) is a polyanionic, chemically modified cyclodextrin derivative that functions as a pharmaceutical solubilizing agent and drug delivery carrier. By forming non-covalent inclusion complexes with lipophilic compounds, SBE-β-CD significantly enhances the aqueous solubility, stability, and bioavailability of poorly soluble active molecules. In cellular and formulation studies, this hydrophilic excipient improves drug dissolution and physical stability without destabilizing lipid membranes at physiological concentrations.
Solubility

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