SMILES:
C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
Chemical Structure
Check the
SB431542
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide | |
|---|---|---|
| CAS Number | 301836-41-9 | |
| Molecular Formula |
C22H16N4O3 |
|
| Molecular Weight (MW) | 384.39 | |
| SMILES | C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 | |
| InChIKey | FHYUGAJXYORMHI-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
77 mg/mL
(200.31 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
| DMSO |
13 mg/mL
(33.81 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
| DMSO |
10 mg/mL
(26.01 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(260.15 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
| DMSO |
77 mg/mL
(200.31 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 9 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- SB431542 Mechanism of Action: ALK5 Inhibition in Pluripotent Stem Cell Research
- SB431542: Selectivity & Specificity
- SB431542 Working Concentration | Cell Culture | Treatment
- SB431542 Solubility in DMSO
- SB431542 Stock Solution
- SB431542 Storage
- SB431542 Stability
- SB431542 VS RepSox (E-616452) | Galunisertib (LY2157299) | A-83-01
- SB431542 Molecular Weight
- SB431542 CAS Number
- SB431542 Chemical Structure (2D and 3D)
- SB431542 Sigma (616461)? Try a better option.
- SB431542 MedChemExpress (HY-10431)? Try a better option.
- SB431542 Tocris (1614)? Try a better option.
- SB431542 Cayman (13031)? Try a better option.
- SB431542 TargetMol (T1726)? Try a better option.
- SB431542 SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.