CAS No. 1477949-42-0

Batch: Purity:99.62
Santacruzamate A (CAY10683) Chemical Structure
Chemical Structure
Check the Santacruzamate A (CAY10683) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name ethyl N-[4-oxo-4-(2-phenylethylamino)butyl]carbamate
CAS Number 1477949-42-0
Molecular Formula

C15H22N2O3

Molecular Weight (MW) 278.35
SMILES CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1
InChIKey HTOYBIILVCHURC-UHFFFAOYSA-N

Ordering Information

Biological Activity

Santacruzamate A (CAY10683) is a potent and selective histone deacetylase (HDAC) inhibitor targeting HDAC2. By blocking HDAC activity, it modulates histone acetylation status and chromatin structure, leading to alterations in gene expression pathways. This downstream epigenetic regulation promotes cell cycle arrest and induces apoptosis, resulting in the inhibition of cellular proliferation in susceptible cell populations. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 56 mg/mL (201.18 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 56 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.