CAS No. 18559-94-9
Batch:
Purity:99.97
Chemical Structure
Check the
Salbutamol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol | |
|---|---|---|
| CAS Number | 18559-94-9 | |
| Molecular Formula |
C13H21NO3 |
|
| Molecular Weight (MW) | 239.31 | |
| SMILES | CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O | |
| InChIKey | NDAUXUAQIAJITI-UHFFFAOYSA-N |
Salbutamol (Albuterol) is a selective beta2-adrenergic receptor agonist that induces bronchodilation. Activation of the beta2-adrenergic receptor stimulates adenylate cyclase, increasing intracellular cyclic AMP (cAMP) levels and leading to protein kinase A activation. This signaling cascade inhibits airway smooth muscle contraction and reduces bronchial tone, effectively relieving bronchospasm associated with respiratory conditions such as asthma and bronchitis. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
47 mg/mL
(196.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.