CAS No. 927871-76-9
Chemical Structure
Check the
S107
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 927871-76-9 | |
|---|---|---|
| Molecular Formula |
C11H15NOS |
|
| Molecular Weight (MW) | 209.31 | |
| SMILES | CN1CCSC2=C(C1)C=C(C=C2)OC |
Biological Activity
S107 is a small-molecule stabilizer of the type 1 ryanodine receptor (RyR1). By binding to RyR1, it enhances the binding affinity of calstabin-1 (FKBP12) to the receptor complex. This targeted channel stabilization prevents abnormal sarcoplasmic reticulum intracellular calcium leakage, thereby restoring physiological calcium homeostasis and mitigating muscle fatigue and weakness in skeletal muscle preclinical models. [1]
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Note: Technical data last updated: Sep 1, 2026.