CAS No. 113665-84-2
Batch:
Purity:98.62
Chemical Structure
Check the
(S)-Clopidogrel
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate | |
|---|---|---|
| CAS Number | 113665-84-2 | |
| Molecular Formula |
C16H16ClNO2S |
|
| Molecular Weight (MW) | 321.82 | |
| InChIKey | GKTWGGQPFAXNFI-HNNXBMFYSA-N |
Biological Activity
(S)-Clopidogrel is an inhibitor of the P2Y12 receptor that exerts potent antiplatelet and anticoagulant effects. Upon metabolic activation, it selectively binds to the P2Y12 receptor to block ADP-mediated signaling, thereby suppressing ADP-induced platelet aggregation. In preclinical models, this P2Y12 inhibition attenuates downstream pro-inflammatory and pro-fibrotic pathways, demonstrating anti-inflammatory and antifibrotic properties in chronic kidney disease and liver fibrosis. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
64 mg/mL
(198.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 64 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.